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GREWAL EYE INSTITUTE Initial TO Give C3R CROSSLINKING TREATMENT IN THE Entire INDIAN SUB-CONTINENT
"C3R crosslinking only treatment to halt progression of Keratoconus," says Dr SPS Grewal
C3R Crosslinking, Most recent Advancement in Ophthalmology, Internationally Launched This Month, Ray of Hope for Lacs of Indian Keratoconus Patients
Chandigarh, September 27, 2006 (InfoMailers.com) --Grewal Eye Institute (GEI), the premier comprehensive Eye Care Institute based at Chandigarh, has achieved a new high in bringing the latest technological advancement in the field of eye care, by becoming the first and the only institute, not only in India, but in the entire Indian Sub-Continent to give the revolutionary 'Corneal Collagen Crosslinking with Riboflavin' (C3R) Treatment to the masses. The C3R procedure, the only recognized treatment that has lately been proven to permanently halt the progression of the dreaded Keratoconus illness, was commercially launched globally in the second week of this month itself. By procuring this as soon as-in-a-decade technological break-by means of in less than two weeks of its launch, GEI is now 1 of the couple of eye institutes in the world and the only in Indian subcontinent, to offer comprehensive treatment now obtainable for this previously untreatable illness. This was announced here nowadays by Dr. SPS Grewal, CEO, GEI.
The C3R Treatment is a ray of hope for lacs of Indian Keratoconus Patients, who, just before the launch of this advanced procedure, had been resigned to the vagaries of fate. This is because Keratoconus is amongst the most dreaded of eye diseases, as in most of the circumstances, the disease progresses relentlessly throughout the young age, does not have any acute symptoms initially and thus is frequently not detected in the early stages. In the advanced stages, the only treatment alternatives available earlier had been surgical insertion of 'Intacs' or a 'Corneal Transplant', both of which have limited success on a lot of grounds, like trauma to the eye, several precautions needed post-surgery and a lengthy recovery period etc. Most importantly, from both the doctors' & patients' perspective, neither of the operations guaranteed a stoppage of the disease. There was often the possibility of setting in of Keratoconus again, even right after the operation. This made the scenario a frustrating 1 for both the patient and the doctor.
Speaking at the press conference Dr S.P.S. Grewal, (CEO), GEI said, "C3R is a non-surgical procedure. Also it is the only identified procedure that is proven to halt the progression of the dreaded Keratoconus. This treatment now provides an end to a lifetime of waiting and uncertainty for Keratoconus patients. This is a straightforward 1-time treatment that provides a permanent solution to Keratoconus. It does not need heavy precautions or typical follow-up visits, does not want an eye donor as necessary in 'Corneal Transplant', does not call for any stitches or incision in the eye, takes just around 1 hour and the patient recovery is fast. This procedure is a boon for patients with keratoconus".
Keratoconus weakens the cornea of the eye causing the eye to bulge outwards and producing moderate to severe blurriness of vision. In the C3R process, the eye is impregnated with a riboflavin solution and exposed to ultra-high frequency light. C3R causes the collagen fibrils to thicken, stiffen, and crosslink & re-attach to each other, generating the cornea stronger and far more stable therefore convincingly halting the progression of the disease. This method can also be employed in corneal ulcers and before LASIK treatment in high Myopes to minimize the risk of postoperative Keratectasia.
Like all treatments, this process is most beneficial when performed at the earliest possible stage of Keratoconus when the visual and mechanical harm to the cornea is minimal. This is where the role of modern day topography devices such as the Pentacam lies. The Pentacam helps to detect Keratoconus significantly before it can be detected in a clinical examination and ensures that the disease is permanently halted by C3R prior to any serious harm to the eye.
The C3R process was launched internationally at the 24th Congress of the European Society of Cataract and Refractive Surgeons (ESCRS) held at London from September 9-13, 2006 where Dr SPS Grewal and team presented their analysis work on Pentacam.
Speaking at the press conference DR SPS Grewal said, "It is often our endeavour to bring the finest, safest and the newest technologies & advancements in the field of eye care to patients in our region. The continued faith, patronage and trust of our patients in the region, nationally and internationally, inspires us to continue to push the limits of excellence and community service here at GEI. We are extremely happy to be the 1st and only institute in the Indian Sub-Continent to provide the C3R process. For the field of Opthhalmology the treatment of Keratoconus is as considerable as bypass surgery or angioplasty in cardiology. It is matter of excellent satisfaction to us that our patients will be amongst the first to benefit from this revolutionary procedure. These days we reaffirm our commitment to lead the way in procuring and advancing cutting-edge solutions to eye diseases." ***
Keratoconus and C3R - A Couple of Details
Keratoconus
Keratoconus is a degenerative non-inflammatory disorder of the eye in which structural modifications inside the cornea trigger it to thin and change to a a lot more conical shape than its typical gradual curve. Keratoconus can cause substantial distortion of vision, with several images, streaking and sensitivity to light all usually reported by the patient. Although frequently thought of as a rare condition, Keratoconus is the most frequent dystrophy of the cornea, affecting around one individual in a thousand. It is usually diagnosed in the patient's adolescent years and attains its most severe state in the twenties and thirties. The course of its progression following diagnosis is unpredictable. If in both eyes, the deterioration in vision linked with the illness can impact the person's capacity to drive a car or read typical print. Over 90% of patients have involvement of both eyes, although it is not unusual for there to be asymmetric changes, with 1 eye being a lot more involved than the other.
The abnormal curvature of the cornea due to Keratoconus modifications the cornea's refractive error producing moderate to severe blurriness of vision. Keratoconus is an irregular protrusion of the cornea, the clear surface over the colored part of the eye. It is comparable, structurally, to the crystal of a watch. If this crystal or windowpane is not smooth, the light will not bend evenly and an irregular image will be formed, like searching through a bumpy piece of glass.
Diagnosis of Keratoconus
The only clue to a Keratoconus diagnosis could be from corneal measurements or a corneal topography map. A topographical map of the cornea will show the high and low spots on the cornea, much like a topographical map of the earth will show the mountains and oceans. This is where the role of modern topography devices like the Pentacam lies. The Pentacam helps to detect Keratoconus considerably just before it can be detected in a clinical examination.
'Corneal Collagen Crosslinking with Riboflavin' (C3R)
The most recent revolutionary Keratoconus treatment is C3R (Corneal Collagen Crosslinking with Riboflavin) that has been proven to strengthen the weak corneal structure. This strategy works by increasing collagen crosslinking, which are the natural "anchors" inside the cornea. These anchors are responsible for preventing the cornea from bulging out and becoming steep and irregular, consequence of advanced Keratoconus. C3R causes the collagen fibrils to thicken, stiffen, and crosslink & reattach to each and every other, making the cornea stronger and far more stable thus provenly halting the progression of the disease. This method can also be utilized in corneal ulcers and before LASIK treatment in high Myopes to minimize the risk of postoperative Keratectasia.
The Procedure
The C3R treatment is performed in just 30 minutes. In the course of the treatment, custom-produced riboflavin eye drops are applied to the cornea, which is then activated by ultraviolet light. This amazingly easy method has been shown in laboratory and clinical studies to increase the amount of collagen cross-linking in the cornea and strengthen the cornea.
The Advantages of C3R over other remedies
Contact Lenses - RGP Contact Lenses
In mild or early stages, eyeglasses or typical contact lenses could right the astigmatic vision. Contact lenses in Keratoconus are not straightforward to fit, generally not quite comfy. They will need constant maintenance and frequent follow ups with the physician. As Keratoconus advances, rigid gas-permeable (RGP) contact lenses possibly the only non-surgical way to obtain clear vision. But contact lens fitting of a patient with Keratoconus demands much care and frequent check-ups, because the condition can worsen. Most importantly, they do not arrest the progress of disease. Also there can be scarring as a result of contact lens wear causes troubles of its own.
Intacs
A recent surgical option to corneal transplant is the insertion of intrastromal corneal ring segments. A small incision is produced in the periphery of the cornea and two thin arcs of polymethyl methacrylate slid between the layers of the corneal stroma on either side of the pupil, the incision then becoming closed. The segments push out against the curvature of the cornea, flattening the peak of the cone and returning it to a more natural shape. Even so intacs do not inherently alter the biomechanical structural integrity of the cornea and thus may not be a permanent remedy. If the refraction adjustments over a period of time right after inserting the intacs rings they would want to be removed. Another advantage of C3R over Intacs is that C3R does not involve any incisions as in Intacs.
Corneal Transplant
A corneal transplant may be needed when vision can't be corrected satisfactorily making use of other procedures such as contact lenses and glasses, or if painful swelling can't be relieved by medications. A corneal transplant, also known as a corneal graft, or as a penetrating Keratoplasty, involves the removal of the central portion referred to as a button of the diseased cornea and replacing it with clear healthy donor button. The donor cornea button is sewed into the defect created by removal of the diseased cornea. But a corneal transplant is dependent on eye donation and needs a long healing period. The recovery of vision might not be quite very good. Lengthy term studies show that Keratoconus can recur even following Keratoplasty.
Adavantages of C3R
Simple one time treatmentNo periodic treatments requiredHalts the progress and causes some regressionIt is permanentNo handling of lenses every dayDoes not want any eye donationNo precautionNo injectionNo stitches as in KeratoplastyNo incisions as in IntacsQuick recovery, short follow up.
For Further Details, Please Contact ::
Hospital Contact ::
Dr. S. P. S. Grewal(Former Associate Professor, Deptt. of Ophthalmology, PGIMER, Chandigarh)Grewal Eye InstituteThe Premiere Institute for Total Eye Care(ISO 9001:2000 Certified)SCO 168-169, Sector 9-C, Madhya Marg, Chandigarh - 160 009 (India)Ph : +91-172-2747118, 5193969Fax : +91-172-2744843Mail : drgrewal@gmail.comWeb site : http://www.lasikgei.com
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